How to file income tax return without form-16?

I have not filed income tax for 2 years and I want to do this now.

Unfortunately, I lost form 16 for year 2006-2007 due to postal mail. Is there any way to file income tax without form-16 for this year?

Also, for year 2007-2008, I have e-Form16. How do I file IT return with e-Form16? (It is a signed PDF document).